Retrospective study on calcium antagonist therapy in more than 11,000 Danes

Danish researchers analyzed the data related to dihydropyridine calcium-antagonists (such as nifedipine, felodipine, nicardipine) in the Danish national healthcare database, comparing 1931 subjects with Parkinson’s disease to 9651 subjects of same age and gender without the disease.  They established that the risk of developing Parkinson’s disease was 27% lower in subjects on treatment with dihydropyridine calcium-antagonists, independently of dosage or duration of treatment.

Source:  Ritz B et al Ann Neurol online December 2009