Report on the meeting held at Buenos Aires to relaunch the World Parkinson Disease Association, with the co-operation of the Grigioni Foundation for Parkinson's disease and all the associations in South America.
The participants to the meeting for the relaunch of the World Parkinson Disease Association held in Buenos Aires included the President of the Grigioni Foundation for Parkinson's disease in Italy and the Presidents of all the Associations of patients with Parkinson’s disease in South America.
read full report |
Reduction in cholinergic activity evident in PET images
Brain images of 44 patients with Parkinson’s disease, out of whom 17 had a history of repeated falls, and 15 health subjects were obtained by PET techniques using markers of dopaminerigc and cholinergic activity. Cholinergic activity was significantly lower in the cerebral cortex of patients vs subjects, especially in the patients with a history of repeated falls (patients who had fallen -12.3%, patients who had not -6.6%), whereas there were no differences between the patients who had fallen and those who had not in terms of dopaminergic activity. A 11.8% reduction in cholinergic activity in the thalamus was recorded only in the patients who had fallen.
Source: Bohnen N et al Neurology 2009; 17: 1670-1676 |
|
Retrospective study on calcium antagonist therapy in more than 11,000 Danes
Danish researchers analyzed the data related to dihydropyridine calcium-antagonists (such as nifedipine, felodipine, nicardipine) in the Danish national healthcare database, comparing 1931 subjects with Parkinson’s disease to 9651 subjects of same age and gender without the disease. They established that the risk of developing Parkinson’s disease was 27% lower in subjects on treatment with dihydropyridine calcium-antagonists, independently of dosage or duration of treatment.
Source: Ritz B et al Ann Neurol online December 2009 |
|
Only exception: abnormal eating
1167 patients with Parkinson’s disease in South Corea were administered the Minnesota questionnaire to detect abnormal compulsions. 10% had abnormal compulsions, especially punding (tidying, cleaning and cataloging objects without any purpose) (4.2%), eating (3.4%), sexual behaviors (2.8%), shopping (2.5%) and gambling (1.3%). All these abnormal behaviors were related to the dose of dopamine agonist taken, except punding, which was related to the dose of levodopa, and eating, which was not related to the dose of any drug.
Source: Lee JY et al Parkinsonism Relat Disord online 15 December 2009 |
|
|
|
|
<< Start < Prev 1 2 3 4 5 Next > End >>
|
|
Page 2 of 5 |
